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Lean Into It

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Lean Into It

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Editorial Reviews

Reissue. Lean into It is the second studio album by the hard rock supergroup Mr. Big, released in March 26, 1991. The band's breakthrough release, Lean into It peaked at #15 on the Billboard 200 charts, while the single "To Be with You" became the band's first and only song to hit #1 on the Billboard Hot 100. The follow-up single, "Just Take My Heart", was another Top 40 hit, peaking at #16 on the Billboard Hot 100. "Daddy, Brother, Lover, Little Boy" features Gilbert and Sheehan running Makita cordless drills over their guitar strings in harmony to create an unusually fast solo which is likely not possible to replicate with hands. The cover image is a picture from the Montparnasse train accident that occurred on October 22, 1895 in Gare Montparnasse station in Paris, France.

Lean Into It

Shining a spotlight on dementia research this September

What's on

New scientific discoveries, new hope to stop dementia

Our plans

See how our science is tackling dementia

Lab profiles

Come join us in transforming dementia research

Vacancies
Research partners

The Dementia UK Ecosystem (DUKE) brings together leaders from the UK DRI, Dementias Platform UK, the National Institute for Health Research, the pharmaceutical industry, and funders to create a cohesive community, coordinating efforts to accelerate progress in tackling dementia.

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Government

Produced by a cross-party group of MPs and Peers in collaboration with Alzheimer’s Society, the 'Fuelling the Moonshot' report is the culmination of a detailed inquiry run by the All-Party Parliamentary Group (APPG) on Dementia, which received evidence from experts and organisations in the field of dementia research. The report makes a case for how the Government’s promised ‘Dementia Moonshot’ funding should be spent to best support research into dementia and neurodegeneration.

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Awards

Prof Sir David Klenerman, UK DRI Group Leader at Cambridge, and Prof Sir Shankar Balasubramanian have been awarded the 2022 Breakthrough Prize for their development of Next Generation Sequencing. The groundbreaking technology significantly reduced the time and cost associated with sequencing a human genome, revolutionising modern research and medicine.

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Science Vision

We accelerate, innovate, deepen and broaden discovery science in dementia, with the goal of filling the huge knowledge gap in this field. We exist to bring forward the day when research benefits people living with and those at risk of dementia.

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Translation and innovation

We have a clearly defined vision at the UK DRI to develop effective therapeutics, diagnostics and technologies for people living with dementia. Alongside building our disease knowledge over the coming years, we will also make progress in translating these discoveries into the clinic.

Translation and innovation
Research themes

We study a range of neurodegenerative disorders that cause dementia. Many of them share fundamental disease mechanisms and characteristics, and greater understanding gained in one can often benefit others. To ensure we capitalise on diverse expertise, approaches and perspectives, we have established cross-centre themes.

Research themes
Equity, Diversity and Inclusion

Our efforts to increase the diversity of our team, ensure inclusion and promote equality of opportunity, align with our vision for the UK DRI’s Institute culture and identity as a world-leader in dementia research.

Equity, Diversity and Inclusion

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